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Question
The regions of an antibody that make it distinct from all other kinds of antibodies are its ______ regions.
Fill in the Blanks
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Solution
The regions of an antibody that make it distinct from all other kinds of antibodies are its variable (V) regions.
Explanation:
Each antibody molecule has variable (V) regions at the terminal portions of both heavy and light chains. These variable regions show considerable variation in amino acid sequences, which allows each antibody to specifically bind to a unique antigen. In contrast, the constant (C) regions are relatively conserved and dictate the class of the antibody. Thus, the variable regions determine the antigen specificity and make each antibody distinct from others.
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