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Questions
Redraw the flow-chart with corrections. Explain in brief the process of obtaining energy through oxidation of carbohydrates, lipids & proteins.

How energy is formed from oxidation of carbohydrates, fats and proteins? Correct the diagram given below.

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Solution 1
Corrected flow-chart:

Process of obtaining the energy:
- Carbohydrates: Carbohydrates such as glucose are broken down into pyruvic acid through glycolysis. Pyruvic acid is then converted into acetyl-Coenzyme A (Acetyl-CoA), which enters the Krebs cycle and is oxidised. The NADH2 and FADH2 produced during this process are oxidised in the electron transport chain, releasing energy as ATP.
- Proteins: Proteins are digested into amino acids. These amino acids are converted into intermediates that enter the Krebs cycle, often through acetyl-CoA. During the Krebs cycle, NADH2 and FADH2 are formed, which are oxidised in the electron transport chain to produce ATP.
- Lipids: Lipids are broken down into fatty acids and glycerol. Fatty acids are converted into acetyl-CoA, which enters the Krebs cycle and is oxidised. The NADH2 and FADH2 produced are then oxidised through the electron transport chain, resulting in the release of energy as ATP.
Solution 2
- Dietary carbohydrates are digested by enzymes and transformed into glucose. Proteins and lipids are metabolised into amino acids and glycerol, respectively.
- Carbohydrates are oxidised during cellular respiration. Aerobic respiration involves three processes for glucose oxidation: glycolysis, the tricarboxylic acid cycle (Krebs cycle), and the electron transfer chain.
- During glycolysis, one molecule of glucose yields two molecules of pyruvic acid, ATP, NADH2, and water. The process converts pyruvic acid into Acetyl-Coenzyme-A, releasing two molecules of NADH2 and CO2.
- In the TCA cycle, molecules of Acetyl-CoA enter mitochondria and undergo a series of cyclic events. The acetyl portion of Acetyl-CoA is totally oxidised throughout this cyclical phase. This reaction releases chemicals such as CO2, H2O, NADH2, and FADH2.
- In the third step of the ETC reaction, NADH2 and FADH2 from the first two steps are used to produce ATP molecules. Each NADH2 molecule yields 3 ATP molecules, while FADH2 yields 2 ATP molecules.
- When one molecule of glucose is completely oxidised in the presence of oxygen, it produces 38 molecules of ATP, which is how carbohydrates are converted into energy.
- Insufficient carbohydrates in the diet might lead to the use of protein or lipids for energy. Acetyl-CoA is produced by the conversion of fatty acids from lipids and amino acids from proteins. Acetyl-CoA can be oxidised through the TCA cycle to produce energy.

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