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Questions
Redraw the flow-chart with corrections. Explain in brief the process of obtaining energy through oxidation of carbohydrates, lipids & proteins.

How energy is formed from oxidation of carbohydrates, fats and proteins? Correct the diagram given below.

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Solution 1
Corrected flow-chart:

Process of obtaining the energy:
- Carbohydrates: Carbohydrates like glucose are oxidized to pyruvic acid. Pyruvic acid is converted to acetyl-co-enzyme-A which is oxidized through Kreb’s cycle. The molecules of NADH2 produced during this are oxidized through electron transfer chain reaction and finally, energy is obtained.
- Proteins: Proteins are digested to amino acids and amino acids are converted into acetyl-co-enzyme-A. Acetyl-co-enzyme-A is oxidized through Kreb’s cycle. The molecules of NADH2 produced during this are oxidized through electron transfer chain reaction and finally, energy is obtained.
- Lipids: Lipids are converted to fatty acids and fatty acids to acetyl-co-enzyme-A. Acetyl-co-enzyme-A is oxidized through Kreb’s cycle. The molecules of NADH2 produced during this are oxidized through electron transfer chain reaction and finally, energy is obtained.
Solution 2
- Dietary carbohydrates are digested by enzymes and transformed to glucose. Proteins and lipids are metabolised into amino acids and glycerol, respectively.
- Carbohydrates are oxidised during cellular respiration. Aerobic respiration involves three processes for glucose oxidation: glycolysis, tricarboxylic acid cycle (Kreb's cycle), and electron transfer chain.
- During glycolysis, one molecule of glucose yields two molecules of pyruvic acid, ATP NADH2, and water. The process converts pyruvic acid into Acetyl-Coenzyme-A, releasing two molecules of NADH2 and CO2.
- In the TCA cycle, molecules of Acetyl-Co-A enter mitochondria and undergo a series of cyclic events. The acetyl portion of Acetyl-Co-A is totally oxidised throughout this cyclical phase. This reaction releases chemicals such as CO2, H2O, NADH2, and FADH2.
- In the third step of the ETC reaction, NADH2 and FADH2 from the first two steps are used to produce ATP molecules. Each NADH2 molecule yields 3 ATP molecules, while FADH2 yields 2 ATP molecules.
- When one molecule of glucose is completely oxidised in the presence of oxygen, it produces 38 molecules of ATP, which is how carbohydrates are converted into energy.
- Insufficient carbohydrates in the diet might lead to energy generation from proteins or lipids. Acetyl-Co-A is produced by the conversion of fatty acids from lipids and amino acids from proteins. Acetyl-Co-A can produce energy through the TCA cycle.

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