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Question
‘Mongoloid idiocy’ occurs due to ______.
Options
monosomy of sex chromosomes
monosomy of 21st pair of autosomes
trisomy of sex chromosomes
trisomy of 21st pair of autosomes
MCQ
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Solution
‘Mongoloid idiocy’ occurs due to trisomy of 21st pair of autosomes.
Explanation:
‘Mongoloid idiocy’ is an outdated term for Down’s syndrome, which is caused by the presence of an extra (third) chromosome 21, hence trisomy 21. This occurs due to non-disjunction during gamete formation, resulting in 47 chromosomes instead of the normal 46. Affected individuals have characteristic physical features and mental retardation associated with this chromosomal abnormality.
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