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How many recessive alleles must a female possess to express an X-linked recessive trait like haemophilia?

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Question

How many recessive alleles must a female possess to express an X-linked recessive trait like haemophilia?

Options

  • Three or more recessive alleles across both chromosomes

  • Two recessive alleles, one on each X chromosome

  • A single recessive allele inherited from the father

  • Only one recessive allele on one X chromosome

MCQ
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Solution

Females possess two X chromosomes. To express an X-linked recessive trait, they must be homozygous recessive, meaning both X chromosomes carry the recessive allele. A female with only one recessive allele is a carrier and does not express the trait phenotypically.

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