Question

How many double-stranded RNA regions are formed during the folding process of tRNA into its cloverleaf structure?

Options

• Four regions of double-stranded RNA

• Five or more regions of double-stranded RNA

• Three regions of double-stranded RNA

• Two regions of double-stranded RNA

Answer 1

Four regions of double-stranded RNA are formed during the folding of tRNA into its cloverleaf secondary structure. These double-stranded stems provide structural stability and are separated by single-stranded loops (DHU loop, anticodon loop, TΨC loop, and variable loop) that contain functionally important sequences.