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Question
How are gene mutations different from chromosomal aberrations? Give one example of each.
Very Short Answer
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Solution
A gene mutation changes the DNA sequence within a gene; sickle-cell anaemia is an example. A chromosomal aberration changes chromosome structure or number and may affect many genes; trisomy 21 in Down's syndrome is an example.
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Chapter 6: Chromosomes, Sex-Linked Inheritance and Human Genetic Disorders - EXERCISES [Page 322]
