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Give scientific reasons: α-Amino acids have high melting points compared to the corresponding amines or carboxylic acids of comparable molecular mass.

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Questions

Give scientific reasons:

α-Amino acids have high melting points compared to the corresponding amines or carboxylic acids of comparable molecular mass.

Why α-amino acids have high melting points compared to the corresponding amines or carboxylic acids of comparable molecular mass?

Short/Brief Note
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Solution

  1. This is due to the peculiar structure called zwitter ion structure of α -amino acids.
  2. α-Amino acid molecule contains both acidic carboxyl (–COOH) group as well as basic amino (–NH2) group.
  3. Proton transfer from the acidic group to the basic group of amino acid forms a salt, which is a dipolar ion called zwitter ion.

Thus, α-amino acids have high melting points compared to the corresponding amines or carboxylic acids of comparable molecular mass.

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Chapter 14: Biomolecules - Exercises [Page 320]

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