Question

Explain 'Wobble hypothesis' with the help of a suitable diagram.

Answer 1

Wobble Hypothesis:
(1) This hypothesis suggests that, in codon-anticodon pairing, the third base may not be complementary. The third base of the codon is called wobble base and this position is called wobble position.
(2) The actual base pairing occurs at first two positions only.

c. In the above example through the codon & anticodon do not match perfectly then also the required amino acid is brought perfectly. This enables the economy of tRNA. GUU, GUC, GUA & GUG – codons.
CCA – anticodon for all 4 codons.