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Question
Explain in brief the process of hybridization in DNA fingerprinting.
Explain
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Solution
Probe DNA is added to the nitrocellulose filter paper containing host DNA. The single-stranded DNA probe pairs with the complementary base sequence of the host DNA strand. As a result DNA-DNA hybrids are formed on the nitrocellulose filter paper. Remaining single stranded DNA probe fragments are washed off.
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