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Questions
Draw a neat and labelled diagram of transcription and processing of hn-RNA
Explain processing of hn-RNA with the help of neat and labelled diagram.
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Solution 1

Solution 2
- In eukaryotes, forms of RNA transcribed from DNA are called primary transcripts. Such transcripts undergo changes called processing or maturation before becoming functional.
- The primary transcript is non-functional and contains both exons and introns.
- During processing, only introns are removed by the process called splicing.
- Exons are joined in a definite sequence (order) by the DNA ligase enzyme.
- Heterogeneous nuclear RNA undergoes the process of capping and tailing.
- In capping, methylated guanosine triphosphate is added to the 5’ end of hnRNA.
- In tailing, polyadenylation (addition of multiple adenine nitrogen bases) takes place at 3’end.
- It is the fully processed hnRNA, now called m-RNA.

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Multiple Choice Question:
Transcription is the transfer of genetic information from _______.
The enzyme ______ forms the peptide bond between amino acid on the first initiator t-RNA at P-site and amino acid on t-RNA at A-site.
A mature mRNA consists of 900 bases without any stop codon in between. What would be the number of amino acids coded by this mRNA during translation?
Identify the property of genetic code represented by the following case:
Each codon codes for a particular amino acid.
Study the following statements and select the correct option.
Statement A: The primary transcript produced in eukaryote is translated without undergoing any modification or processing.
Statement B: The hnRNA in humans has exons and introns.
Identify the nucleotide sequence of the mRNA which codes for the sequence of amino acids 'Met-Leu- Val- Arg- Ala'.
____________ carries the message for formation of polypeptide chain.
In a eukaryotic transcription and translation take place ______.
During taling process number of adenylate residues added at 3' end of hnRNA.
Who proposed the Central Dogma of molecular biology and in which year?
