Question

Disulphide bonds link the polypeptide chains of antibodies together. What type of additional stabilisation helps maintain antibody structure?

Options

• Ionic interactions only

• Peptide bonds between chains

• Hydrogen bonds only

• Non-covalent interactions between chains

Answer 1

Beyond disulphide bonds, antibody structure is further stabilized by non-covalent interactions between chains. These non-covalent interactions include hydrogen bonds, ionic interactions, and hydrophobic interactions, which collectively contribute to the overall stability and integrity of the Y-shaped antibody molecule.