Question

Distinguish between Glycolysis and TCA cycle.

Answer 1

	Glycolysis	TCA cycle/Krebs cycle
1.	The process of glycolysis occurs in the cytoplasm of the cell.	Krebs cycle takes place in mitochondria.
2.	In glycolysis, one molecule of glucose is oxidised step-by-step to produce two molecules each of pyruvic acid, ATP, NADH2, and water.	In the Krebs cycle, a molecule of acetyl-CoA is completely oxidised, and in the process, CO2, H2O, NADH2, FADH2, and ATP are produced.
3.	Glycolysis can take place in both aerobic and anaerobic respiration.	Krebs cycle takes place only during aerobic respiration.
4.	The first step in cellular respiration is glycolysis, where glucose is converted into pyruvate.	The second step in cellular respiration is the Krebs cycle.
5.	Two molecules of pyruvate are obtained in glycolysis.	Pyruvate is converted into CO2 and H2O during the Krebs cycle.
6.	Two ATP molecules are used up in glycolysis.	ATP molecules are not used up in Krebs cycle.
7.	Four molecules of ATP are produced in glycolysis.	Two molecules of ATP are produced in the Krebs cycle.
8.	CO2 is not produced during glycolysis.	CO2 is produced in the Krebs cycle.