Question

Differentiate between Klinefelter’s syndrome and Down’s syndrome.

Answer 1

Klinefelter’s Syndrome	Down’s Syndrome
Klinefelter’s syndrome is a sex chromosome disorder (47, XXY) characterized by infertile males with underdeveloped testes, sparse body hair, and mental defects.	Down’s syndrome is an autosomal disorder (trisomy 21) causing mental retardation, distinct facial features, and heart defects. Both have 47 chromosomes but differ in chromosome type affected and symptoms.