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Question
Describe the processing of hnRNA to mRNA in Eukaryotes.
Very Long Answer
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Solution
- Primary transcripts, also known as heterogeneous nuclear RNA (hnRNA), are RNAs that are transcribed from DNA in eukaryotes.
- The primary transcript, which has both exons and introns, is non-functional.
- As a result, before it becomes functional, it goes through processing or maturation. Capping, tailing, and splicing are all steps in the process.
- Methylated guanosine triphosphate is added to the 5 end of heterogeneous nuclear RNA during the capping step.
- Polyadenylation occurs at the third end of tailing.
- The technique known as splicing eliminates only introns.
- The RNA ligase enzyme joins exons in a certain order.
- After being fully processed, hnRNA is referred to as m-RNA, which is later exported from the nucleus via the nuclear pore in order to be translated.
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