Question

Assertion (A): A patient of ADA-deficiency requires periodic or repeated infusion of genetically-engineered lymphocytes. 

Reason (R): Lymphocytes are not immortal, but have life span.

Options

• Both (A) and (R) are true and (R) is the correct explanation of (A).

• Both (A) and (R) are true, but (R) is not the correct explanation of (A).

• (A) is true, but (R) is false.

• (A) is false, but (R) is true.

Answer 1

Both (A) and (R) are true and (R) is the correct explanation of (A).

Explanation:

A hereditary condition known as ADA (adenosine deaminase) deficiency impairs immunity. Injecting the patient with genetically altered cells that can momentarily synthesize the absent enzyme is a typical treatment. However, the treatment must be repeated frequently because lymphocytes have a short lifespan.