Question

Anthony is a scientist who has been provided with raw materials to obtain a specific biological Product in large quantities. His laboratory has two large vessels for this purpose - one with a sparger and the other vessel with a stirrer.

Which vessel will be more advantageous to Anthony? Why?

Answer 1

• The Sparged Stirred-tank Bioreactor (with sparger) is more advantageous.
• Compared to a basic stirrer, a sparger significantly increases the oxygen transfer surface area and ensures significantly enhanced oxygen availability by bubbling air directly through the culture medium. Higher cell density and increased productivity result from this.