Question

Among the given compound, the most susceptible to nucleophile attack at the at the carbonyl group

Options

• CH₃COCI

• CH₃CHO

• CH₃COOCH₃

• CH₃COOCOCH₃ 

Answer 1

CH₃COCI 

Explanation:

Among aldehydes and acid derivatives, acid chloride is the most vulnerable to nucleon phallic attack due to the strong and weak ER effect of the a- atom, resulting in carbonyl carbon having the greatest electron deficiency.