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Questions
Illustrate the following reaction giving suitable example in each case:Gabriel phthalimide synthesis
Write the reactions involved Gabriel phthalimide synthesis
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Solution 1
Solution 2
Gabriel Phthalimide Synthesis Used for the preparation of primary amine
Reactions involved in the preparation of primary amine from phthalimide are as follows:
Aromatic primary amines cannot be prepared by this process because aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.
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How are propan-1-amine and propan-2-amine prepared from oxime?
Give the structures of A, B and C in the following reactions :
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Given below are two statements labelled as Assertion (A) and Reason (R).
Assertion (A): Alkyl halides are insoluble in water.
Reason (R): Alkyl halides have halogen attached to sp3 hybrid carbon.
Select the most appropriate answer from the options given below:
Match the reactions given in Column I with the statements given in Column II.
| Column I | Column II | ||
| (i) | Ammonolysis | (a) | Amine with lesser number of carbon atoms |
| (ii) | Gabriel phthalimide synthesis | (b) | Detection test for primary amines. |
| (iii) | Hoffmann Bromamide reaction | (c) | Reaction of phthalimide with \[\ce{KOH}\] and \[\ce{R-X}\] |
| (iv) | Carbylamine reaction | (d) | Reaction of alkylhalides with \[\ce{NH3}\] |
In the given reaction what is the X?
\[\begin{array}{cc}
\ce{O}\phantom{.......................}\\
||\phantom{.......................}\\
\phantom{}\ce{R - C - OH <-[H3O] Χ ->[H] RCH2NH2}
\end{array}\]
A compound 'A' on reduction with iron scrap and hydrochloric acid gives compound 'B' with molecular formula C6H7N. Compound 'B' on reaction with CHCl3 and alcoholic KOH produces an obnoxious smell of carbylamine due to the formation of 'C'. Identify 'A', 'B' and 'C' and write the chemical reactions involved.
What is the IUPAC name of \[\ce{(CH3)2 - N - CH3}\]?
Identify the compo ds A and B in the following reactions:
\[\ce{A ->[Nitrating mixture] B ->[(i) Sn/cone. HCI][(ii) NaOH] Aniline}\]
Write a short note on the following:
Ammonolysis.
