Advertisements
Advertisements
Question
Amides can be converted into amines by the reaction named ______.
Options
Hoffmann degradation
Ammonolysis
Carbylamine
Diazotisation
Advertisements
Solution
Amides can be converted into amines by the reaction named Hoffmann degradation.
Explanation:
The Hofmann-degradation reaction is the process by which NaOH and Br2 transform an amide into a primary amine with one fewer carbon atom than the initial amide.
APPEARS IN
RELATED QUESTIONS
Arrange the following in the increasing order of their pKb values:
C6H5NH2, C2H5NH2, C6H5NHCH3
Explain Hoffmann’s exhaustive alkylation with suitable reactions.
Identify the product 'A' in the following reaction.
\[\ce{Aniline ->[(CH3CO)2O][Pyridine] A}\]
Identify the product obtained, when benzamide is treated with bromine and aqueous sodium hydroxide.
____________ can be prepared exclusively by Gabriel phthalimide synthesis.
Reduction of aromatic nitro compounds using \[\ce{Fe}\] and \[\ce{HCl}\] gives ______.
What is the best reagent to convert nitrile to primary amine?
Write following conversions:
nitrobenzene `->` acetanilide
Acetamide and ethyl amide can be distinguished by reacting with.
Which of the following amines can be prepared by Gabriel phthalimide reaction?
