Question

All of the following except ______ are sources of change in the genome.

Options

• non-disjunction during meiosis

• gene mutations

• chromosomal translocation

• amniocentesis

Answer 1

All of the following except amniocentesis are sources of change in the genome.

Explanation:

• Non-disjunction during meiosis causes changes in chromosome number (aneuploidy), which is a source of genomic change.
• Gene mutations cause changes in the DNA sequence resulting in new genetic variants.
• Chromosomal translocation involves rearrangement of chromosome segments, altering gene order and potentially gene function, thus causing changes in the genome.
• Amniocentesis, however, is a diagnostic procedure used to sample amniotic fluid for prenatal genetic testing; it is not a source of genome change itself but rather a medical test to detect genetic abnormalities.