Advertisements
Advertisements
Question
About 8% of the human male population suffers from colour blindness, whereas only about 0.4% of the human female population suffers from this disease. Write an explanation to show how it is possible.
Advertisements
Solution
Colour blindness is a sex-linked disorder and is caused by a recessive gene located on the X chromosome. The Y chromosome of male does not carry any gene for colour vision and the defect appears in the presence of a single recessive gene (XcY). As a result, colour blindness is more common in males (8%) as compared to females (0.4%).
RELATED QUESTIONS
Match the column-I with column-II and re-write the matching pairs.
| Column-I | Column-II |
| 1. 21 trisomy | a. Turner’s syndrome |
| 2. X-monosomy | b. Klinefelter’s syndrome |
| 3. Holandric traits | c. Down's syndrome |
| 4. Feminized male | d. Hypertrichosis |
Give an account of one Mendelian and one chromosomal disorder you have studied.
Match Column I with Column II and select the correct option:
| Column I | Column II | ||
| p. | Pleiotropy | I. | More than two alleles occur at the same locus on homologous chromosomes |
| q. | Multiple alleles | II. | Expression of both the alleles m heterozygous condition |
| r. | Polygenic | III. | Multiple effect of single gene |
| s. | Co-dominance | IV. | Single phenotypic character influenced by more than two genes |
Thalassemia and sickle cell anaemia are caused due to a problem in globin molecule synthesis. Identify the correct statement from the following.
Sickel-cell anaemia is an example of ______.
Females with Turner’s syndrome have ______.
Rajesh and Mahesh have defective haemoglobin due to genetic disorders. Rajesh has too few globin molecules while Mahesh has incorrectly functioning globin molecules. Identify the disorder they are suffering from.
| Rajesh | Mahesh | |
| A. | Sickle cell anaemia - an autosome linked recessive trait | Thalassemia - an autosome linked dominant trait |
| B. | Thalassemia - an autosome linked recessive blood disorder | Sickle cell anaemia - an autosome linked recessive trait |
| C. | Sickle cell anemia - an autosome linked recessive trait | Thalassemia - an autosome linked recessive blood disorder |
| D. | Thalassemia - an autosome linked recessive blood disorder | Sickle cell anaemia - an autosome linked dominant trait |
Read the following and answer from given below:
Turner's syndrome is an example of monosomy. It is formed by the union of an allosome-free egg and a normal 'X' containing sperm or a normal egg and an allosome-free sperm. The individual has 2n = 45 chromosomes (44 + X0) instead of 46. Such individuals are sterile females who have rudimentary ovaries, underdeveloped breasts, small uterus, short stature, webbed neck, and abnormal intelligence. They may not menstruate or ovulate. This disorder can be treated by giving female sex hormones to women from the age of puberty to make them develop breasts and have menstruation. This makes them feel more normal.
The number of Barr bodies present in a female with Turner's syndrome is ______
Read the following and answer from given below:
Turner's syndrome is an example of monosomy. It is formed by the union of an allosome-free egg and a normal 'X' containing sperm or a normal egg and an allosome-free sperm. The individual has 2n = 45 chromosomes (44 + X0) instead of 46. Such individuals are sterile females who have rudimentary ovaries, underdeveloped breasts, small uterus, short stature, webbed neck, and abnormal intelligence. They may not menstruate or ovulate. This disorder can be treated by giving female sex hormones to women from the age of puberty to make them develop breasts and have menstruation. This makes them feel more normal.
Which of the following statements regarding Turner's syndrome is incorrect?
Lipoprotein lipase deficiency (LPLD)is a genetic disorder in which a person has a defective gene for lipase. This leads to high triglycerides, stomach pain, and fat deposits under the skin. It may eventually affect the liver, pancreas and may also cause diabetes. The disorder occurs if a child acquires defective genes from both parents (autosomal recessive). ERT (enzyme replacement treatment) is one of the treatments offered to patients with LPLD.
-
- What procedure is followed in ERT?
- What could be one possible drawback of ERT?
- How can LPLD be treated using Biotechnology? Elaborate.
