Advertisements
Advertisements
Question
A child suffering from Thalassemia is born to a normal couple. But the mother is being blamed by the family for delivering a sick baby.
- What is Thalassemia?
- How would you counsel the family not to blame the mother for delivering a child suffering from this disease? Explain.
- List the values your counselling can propagate in the families.
Advertisements
Solution
- Thalassemia is a group of autosomal recessive blood disorders characterized by severe anemia as a result of production of faulty haemoglobin chains. Mutations in the genes coding for the alpha, beta or delta chains constituting haemoglobin lead to the synthesis of improperly folded haemoglobin that is incapable of transporting oxygen efficiently.
- Thalassemia is an autosomal recessive disease, which means the mutation is carried on one of the autosomes, so the carrier can be any one of the two parents. It has an equal probability of coming from the mother or the father, so to just blame the mother for the child’s abnormality is unjustified.
- The values counseling can propagate in the families are:
- Give a healthy diet plan to the child.
- Accepting their child with all his/her positives and negatives.
- Neither of the parents is responsible for giving birth to a sick baby.
- The defect is caused by a random change in the genes of the child.
- Encouraging the child to follow his/her treatment regularly and lead a happy and normal life.
- Support the child emotionally by talking about fear, anxiety, and depression or stress the child feels.
RELATED QUESTIONS
Why are color-blindness and thalassaemia categorised as Mendelian disorders? Write the symptoms of these diseases seen in people suffering from them.
Answer the following question.
Both Haemophilia and Thalessemia are blood-related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under.
What are the different characters that develop due to Klinefelter's syndrome?
Match the Column I and Column II and select the correct option.
| List-I | List-II | ||
| i. | Holandric genes | a. | Pleiotropy |
| ii. | Multiple effects of a single gene | b. | Hypertrichosis |
| iii. | Skin colour in man | c. | Multiple Alleles |
| iv. | ABO Blood types | d. | Polygenic inheritance |
The correct answer is
Match Column I with Column II and select the correct option:
| Column I | Column II | ||
| p. | Pleiotropy | I. | More than two alleles occur at the same locus on homologous chromosomes |
| q. | Multiple alleles | II. | Expression of both the alleles m heterozygous condition |
| r. | Polygenic | III. | Multiple effect of single gene |
| s. | Co-dominance | IV. | Single phenotypic character influenced by more than two genes |
If a colour-blind man marries a woman who is homozygous for normal colour vision, the probability of their son being colour-blind is ______.
A person with 47 chromosomes due to an additional Y-chromosome suffers from a condition called ______.
Clotting of blood is to ______.
In Down's syndrome, karyotyping has shown that the disorder is associated with trisomy of chromosome number 21 usually due to ______.
Give the genotype of Klinefelter’s syndrome.
