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प्रश्न
Give an account of post transcriptional modifications of a eukaryotic mRNA.
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उत्तर
The primary transcripts (hn-RNA) contain both the exons and the introns and are non-functional. Hence, it is subjected to a process called splicing where the introns are removed and exons are joined in a defined order. Intron is the portion of gene which is transcribed but not translated. In prokaryotes, hnRNA is absent so splicing in not required. hnRNA undergoes additional processing called as capping and tailing. In capping an unusual nucleotide (methyl guanosine triphosphate) is added to the 5′-end of hnRNA. In tailing, adenylate residues (200 - 300) are added at 3′-end in a template-independent manner. It is the fully processed hnRNA, now called mRNA, that is transported out of the nucleus for translation.
Process of Transcription in Eukaryotes
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संबंधित प्रश्न
Depending upon the chemical nature of the template (DNA or RNA) and the nature of nucleic acids synthesised from it (DNA or RNA), list the types of nucleic acid polymerases.
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Construct and label a transcription unit from which the RNA segment given below has been transcribed. Write the complete name of the enzyme that transcribed this RNA.
With regard to mature mRNA in eukaryotes.
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Refer the given diagram. What does it represent?
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What are the functions of methylated guanasine cap?
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