Advertisements
Advertisements
प्रश्न
Observe the segment of mRNA given below.
(a) Explain and illustrate the steps involved to make fully processed hnRNA?
(b) Gene encoding RNA Polymerase I and III have been affected by mutation in a cell. Explain its impact on the synthesis of a polypeptide, stating the reasons.
Advertisements
उत्तर
(a) The hnRNA undergoes processes called capping and tailing followed by splicing. In capping, an unusual nucleotide is added to the 5'-end of hnRNA methyl guanosine triphosphate. In tailing, adenylate residues (about 200 - 300) are added at the 3'-end in a template-independent manner. Now the hnRNA undergoes a process where the introns are removed and exons are joined to form mRNA called splicing.
(b) The process of translation will not happen, thus the polypeptide synthesis is stopped/hampered.
The reason for the above is:
RNA polymerase I transcribe rRNAs which is the cellular factory for protein synthesis.
RNA polymerase III helps in the transcription of tRNA which is the adaptor molecule that transfers amino acids to the site of protein synthesis.
APPEARS IN
संबंधित प्रश्न
Depending upon the chemical nature of the template (DNA or RNA) and the nature of nucleic acids synthesised from it (DNA or RNA), list the types of nucleic acid polymerases.
Explain the process of transcription in Eukaryotes.
Answer the following question.
Construct and label a transcription unit from which the RNA segment given below has been transcribed. Write the complete name of the enzyme that transcribed this RNA.
Regulatory proteins are the accessory proteins that interact with RNA polymerase and affect its role in transcription. Which of the following statements is correct about regulatory protein?
Methyl guanosine triphosphate is added at 5' end of hn-RNA in a process of ______.
To initiate translation, the mRNA first binds to ______.
On the ribosome, mRNA binds ______ and two sites in the ______ for subsequent amino acids to bind to be close enough to each other for the formation of a peptide bond.
A special feature of viruses is that they:
Which is the “Only enzyme” that has “Capability” to catalyse Initiation, Elongation and Termination in the process of transcription in prokaryotes?
What are the functions of poly-A “tail” in a mature on RNA?
