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प्रश्न
Why cannot aromatic primary amines be prepared by Gabriel phthalimide synthesis?
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उत्तर
Gabriel synthesis is used for the preparation of primary amines. Phthalimide, on treatment with ethanolic potassium hydroxide, forms potassium salt of phthalimide, which on heating with alkyl halide followed by alkaline hydrolysis produces the corresponding primary amine. Aromatic primary amines cannot be prepared by this method because aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.
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संबंधित प्रश्न
How do you convert the following: Ethanenitrile to ethanamine
Accomplish the following conversion:
Benzyl chloride to 2-phenylethanamine
Give the structures of A, B and C in the following reaction:
\[\ce{CH3COOH ->[NH3][\Delta] A ->[NaOBr] B ->[NaNO2/HCl] C}\]
Write the reaction of aliphatic primary amine with nitrous acid.
Give the structures of A, B and C in the following reactions :
Account for the following:
Gabriel phthalimide synthesis is not preferred for preparing aromatic primary amines.
Answer in one sentence.
Which amide does produce ethanamine by Hofmann bromamide degradation reaction?
Answer the following
Identify A and B in the following reactions.
\[\ce{C6H5CH2Br->[alco.][KCN]A ->[Na/ethanol]B.}\]
Identify compound 'B' in following series of reactions?
\[\ce{Acetonitrile ->[Na/alcohol] A ->[NaNO2/dil.HCI] B}\]
____________ can be prepared exclusively by Gabriel phthalimide synthesis.
The reduction of alkyl cyanide with sodium and ethanol to give primary amines is, ____________.
Hoffmann Bromamide Degradation reaction is shown by ______.
Describe Gabriel's phthalimide synthesis. (Give reaction)
The Gabriels' phthalimide synthesis is used in the synthesis of
Reduction of nitro alkanes yields which compound?
When primary amines are treated with HCl, the product obtained is which of the following?
Which of the following CANNOT be prepared by ammonolysis of alkyl halide?
The amine 'A' when treated with nitrous acid gives yellow oily substance. The amine A is ______.
Amides can be converted into amines by the reaction named ______.
Write the name of reduction product formed when ethyl cyanide is treated with sodium and alcohol.
