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प्रश्न
Which property of DNA double helix led Watson and Crick to hypothesise semi-conservative mode of DNA replication? Explain.
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उत्तर
Watson and Crick proposed a semi-conservative mode of DNA replication based on the molecule’s antiparallel, double-stranded structure. They suggested that the two strands of the DNA molecule uncoil and separate, with each strand serving as a template for the production of a new (complementary) strand alongside it. The template and its complement then combine to generate a new double-stranded DNA molecule identical to the original. The sequence of bases that should be present in the new strands is easily predicted because they will be complementary to the bases present in the old strands. A will partner with T, T with A, C with G, and G with C. As a result, two daughter DNA molecules are created that are identical to the parent molecule; each daughter DNA molecule consists of one new and one old strand. This replication mechanism is referred to as semi-conservation because each daughter molecule contains only one conserved parent strand. Later, experiments by Joseph Taylor, Meselson and Stahl verified it.
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संबंधित प्रश्न
In some viruses, RNA is present instead of DNA indicating that ______.
In a DNA strand the nucleotides are linked together by ______.
The fact that a purine base always paired through hydrogen bonds with a pyrimidine base leads to, in the DNA double helix ______.
While analysing the DNA of an organism a total number of 5386 nucleotides were found out of which the proportion of different bases were: Adenine = 29%, Guanine = 17%, Cytosine = 32%, Thymine = 17%. Considering the Chargaff’s rule it can be concluded that ______.
Synthesis of DNA from RNA is explained by ______.
By which bonds the purine and pyrimidine pairs of Complementary Strands of DNA held together?
______ occurs in RNA instead of the nitrogenous base thymine found in DNA.
Which of the following is a purine?
During in vitro synthesis of DNA, a researcher used 2’, 3’ – dideoxy cytidine triphosphate as raw nucleotide in place of 2’-deoxy cytidine. What would be the consequence?
What is the smallest part of a DNA molecule that can be changed by a point mutation?
Which of the following nitrogenous bases is classified as a purine with a double-ring structure?
What structural difference exists between the pentose sugar found in DNA and the pentose sugar found in RNA?
The phosphate group in a nucleotide is attached to which carbon of the pentose sugar?
Which end of a polynucleotide chain contains a free phosphate group?
The 3′ end of a polynucleotide chain is characterized by the presence of:
In a DNA double helix, what is the spatial relationship between the two polynucleotide strands?
In a DNA double helix, where are the nitrogenous bases located?
Why is the name 'deoxyribonucleic acid' appropriate for DNA?
A dinucleotide is formed by linking two nucleotides together. The bond formed between them is:
The phosphate group in a nucleotide is attached to which carbon of the pentose sugar?
In a polynucleotide chain, nucleotides are linked together by which type of bond?
Why is the name 'deoxyribonucleic acid' appropriate for DNA?
A dinucleotide is formed by linking two nucleotides together. The bond formed between them is:
Pyrimidines differ from purines in their basic structural feature. Which statement is correct?
