Question

Pyruvate is converted to Acetyl CoA by the process of ______.

Options

• Oxidative Carboxylation

• Oxidative decarboxylation

• Acetylation and Carboxylation

• Reductive decarboxylation

Answer 1

Pyruvate is converted to Acetyl CoA by the process of  Oxidative decarboxylation.

Explanation:

Pyruvate is converted into Acetyl-CoA by removing a carbon dioxide molecule (decarboxylation) while simultaneously being oxidised (loss of electrons). This reaction is catalysed by the pyruvate dehydrogenase complex and links glycolysis to the Krebs cycle.