Advertisements
Advertisements
Question
Answer the following question.
Two children, A and B aged 4 and 5 years respectively visited a hospital with a similar genetic disorder. The girl A was provided enzyme-replacement therapy and was advised to revisit periodically for further treatment. The girl, B was, however, given a therapy that did not require revisit for further treatment.
How was the girl B cured permanently?
Advertisements
Solution
Girl B was treated with gene therapy through the gene isolated from bone marrow cells producing ADA is introduced into cells at early embryonic stages which are a permanent cure so the patient is cured permanently.
APPEARS IN
RELATED QUESTIONS
Draw the diagram of different types of aneuploidy.
One of the parents of a cross has mutation in its mitochondria. In that cross, that parent is taken as a male. During segregation of F2 progenies that mutation is found in ______.
Mutations result in
Match list I with list II
| List I | List II | ||
| A. | A pair of chromosomes extra with diploid | i) | monosomy |
| B. | One chromosome extra to the diploid | ii) | tetrasomy |
| C. | One chromosome was lost from diploid | iii) | trisomy |
| D. | Two individual chromosomes lose from diploid | iv) | double monosomy |
Match list I with list II
| List I | List II |
| A. A pair of chromosomes extra with diploid | (i) monosomy |
| B. One chromosome extra to the diploid | (ii) tetrasomy |
| C. One chromosome loses from diploid | (iii) trisomy |
| D. Two individual chromosomes lose from diploid | (iv) double monosomy |
Which type of mutation shifts the reading frame of all downstream codons?
What mechanism causes a frameshift mutation?
Which of the following is caused by intrinsic replication errors and tautomeric shifts?
What is the distinction between a deletion and an insertion in terms of chromosomal aberrations?
How does DDT resistance in mosquitoes exemplify the evolutionary importance of mutations?
