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Question
Answer the following question.
Two children, A and B aged 4 and 5 years respectively visited a hospital with a similar genetic disorder. The girl A was provided enzyme-replacement therapy and was advised to revisit periodically for further treatment. The girl, B was, however, given a therapy that did not require revisit for further treatment.
How was the girl B cured permanently?
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Solution
Girl B was treated with gene therapy through the gene isolated from bone marrow cells producing ADA is introduced into cells at early embryonic stages which are a permanent cure so the patient is cured permanently.
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Match list I with list II.
| List I | List II | ||
| A. | A pair of chromosomes extra with diploid | i) | monosomy |
| B. | One chromosome extra to the diploid | ii) | tetrasomy |
| C. | One chromosome loses from diploid | iii) | trisomy |
| D. | Two individual chromosomes lose from diploid | iv) | double monosomy |
Match List I with List II.
| List I | List II | ||
| A. | A pair of chromosomes extra with diploid | i) | monosomy |
| B. | One chromosome extra to the diploid | ii) | tetrasomy |
| C. | One chromosome loses from diploid | iii) | trisomy |
| D. | Two individual chromosomes lose from diploid | iv) | double monosomy |
Match list I with list II.
| List I | List II |
| A. A pair of chromosomes extra with diploid | i) Monosomy |
| B. One chromosome extra to the diploid | ii) Tetrasomy |
| C. One chromosome loses a diploid | iii) Trisomy |
| D. Two individual chromosomes lose their diploid | iv) Double chromosome |
