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प्रश्न
Write the contributions of the following scientists in deciphering the genetic code.
George Gamow; Hargobind Khorana; Marshall Nirenberg; Severo Ochoa
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उत्तर
George Gamow proposed that if 20 amino acids are to be coded by 4 bases, then the code should be made up of three nucleotides.
43 = 64 (42 = 16), which is less than 20; so, the codon was proposed to be a triplet.
Har Gobind Khorana developed a chemical method to synthesize RNA molecules with a defined combination of bases.
Marshall Nirenberg developed cell-free systems for protein synthesis, which helped the code to be deciphered.
Severo Ochoa discovered an enzyme (polynucleotide phosphorylase) which helped in the synthesis of RNA with defined sequences in a template-independent manner.
संबंधित प्रश्न
Name the anticodon required to recognize the following codon: AAU.
Name the anticodon required to recognize the following codon: UAU
The number of base substitution possible in amino acid codons is ______.
AUG on the mRNA will result in the activation of which of the following RNA having the correct combination of amino acids:
| Site A | Site B | |
| A. | UAC | Methionine |
| B. | Methionine | UAC |
| C. | Methionine | AUG |
| D. | AUG | Methionine |
Methionine carrying tRNA has anticodon:
Which amino acid is determined by four genetic codes?
What is the start codon and which amino acid does it code for?
What is the wobble effect in the context of the genetic code?
Which of the following statements correctly describes the universality of the genetic code?
How many codons code for amino acids and how many are stop codons?
