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प्रश्न
What would happen if histones were to be mutated and made rich in acidic amino acids such as aspartic acid and glutamic acid in place of basic amino acids such as lysine and arginine?
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उत्तर
If histone proteins were rich in acidic amino acids instead of basic amino acids then they may not have any role in DNA packaging in eukaryotes as DNA is also negatively charged molecule. The packaging of DNA around the nucleosome would not happen. Consequently, the chromatin fibre would not be formed.
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संबंधित प्रश्न
Which of the following is the CORRECT statement with respect to formation of nucleosome?
In prokaryotes, the enzyme RNA polymerase recognizes the promoter by its ______.
The length of DNA segment having 44 base pairs is ______
Barr body in mammals represents ______.
Which one of the following statements about Histones is wrong?
In an experiment, DNA is treated with a compound which tends to place itself amongst the stacks of nitrogenous base pairs. As a result of which, the distance between two consecutive base increases, from 0.34nm to 0.44 nm. Calculate the length of DNA double helix (which has 2 × 109 bp) in the presence of saturating amount of this compound.
Replication of DNA in eukaryotes is initiated by ______.
Histones are enriched with ______.
The non-condensed, light stained and transcriptionally active segments of chromosomes are called ______.
Who among the following has developed technique to synthesize artificial mRNA with known repeated sequences of two or three nucleotides?
Statement I: In prokaryotes, the positively charged DNA is held with some negatively charged proteins in a region called nucleoid.
Statement II: In eukaryotes, the negatively charged DNA is wrapped around the positively charged histone octamer to form nucleosome.
In the light of the above statements, choose the correct answer from the options given below:
What is the nucleoid in prokaryotic cells?
What is a histone octamer?
Chromatin can be defined as:
The human genome contains approximately how many base pairs per diploid cell?
What is the role of topoisomerase I in prokaryotic DNA packaging?
Describe the hierarchical levels of eukaryotic DNA packaging.
What is the charge characteristic of DNA packaging proteins in both prokaryotes and eukaryotes?
