Advertisements
Advertisements
प्रश्न
Account for the following:
Gabriel phthalimide synthesis is not preferred for preparing aromatic primary amines.
Advertisements
उत्तर
Gabriel phthalimide synthesis not prefered for preparing aromatic primary amines because amine formation involves nucleophilic substituion 2 ( ) SN of alkyl halides by the anion formed by the phthalimide. But aryl halides do not undergo nucleophilic substitution with the anion formed by the phthalimide. As nucleophilic substitution reactions are very difficult in aryl halides.
APPEARS IN
संबंधित प्रश्न
Write a short note on Hoffmann bromamide degradation.
Choose the most correct option.
Which of the following compounds will dissolve in aqueous NaOH after undergoing reaction with Hinsberg reagent?
Identify the major product (B).
Best method for preparing primary amines from alkyl halides without changing the number of carbon atoms in the chain is ______.
Which of the following methods of preparation of amines will give same number of carbon atoms in the chain of amines as in the reactant?
Reduction of nitrobenzene by which of the following reagent gives aniline?
(i) \[\ce{Sn/HCl}\]
(ii) \[\ce{Fe/HCl}\]
(iii) \[\ce{H2 - Pd}\]
(iv) \[\ce{Sn/NH4OH}\]
Which of the following amines can be prepared by Gabriel synthesis.
(i) Isobutyl amine
(ii) 2-Phenylethylamine
(iii) N-methylbenzylamine
(iv) Aniline
Match the reactions given in Column I with the statements given in Column II.
| Column I | Column II | ||
| (i) | Ammonolysis | (a) | Amine with lesser number of carbon atoms |
| (ii) | Gabriel phthalimide synthesis | (b) | Detection test for primary amines. |
| (iii) | Hoffmann Bromamide reaction | (c) | Reaction of phthalimide with \[\ce{KOH}\] and \[\ce{R-X}\] |
| (iv) | Carbylamine reaction | (d) | Reaction of alkylhalides with \[\ce{NH3}\] |
When primary amines are treated with HCl, the product obtained is which of the following?
Which of the following statement(s) is/are incorrect in case of Hofmann bromamide degradation?
