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प्रश्न
Account for the following:
Gabriel phthalimide synthesis is not preferred for preparing aromatic primary amines.
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उत्तर
Gabriel phthalimide synthesis not prefered for preparing aromatic primary amines because amine formation involves nucleophilic substituion 2 ( ) SN of alkyl halides by the anion formed by the phthalimide. But aryl halides do not undergo nucleophilic substitution with the anion formed by the phthalimide. As nucleophilic substitution reactions are very difficult in aryl halides.
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संबंधित प्रश्न
Illustrate the following reaction giving suitable example in each case:Gabriel phthalimide synthesis
Identify the product obtained, when benzamide is treated with bromine and aqueous sodium hydroxide.
Identify 'A' and 'B' in the following conversions.
\[\ce{CH3 - I ->[Alc. KCN][\Delta] A ->[Na/C2H5OH] B}\]
Given below are two statements labelled as Assertion (A) and Reason (R).
Assertion (A): Alkyl halides are insoluble in water.
Reason (R): Alkyl halides have halogen attached to sp3 hybrid carbon.
Select the most appropriate answer from the options given below:
The best reagent for converting 2–phenylpropanamide into 2-phenylpropanamine is ______.
Under which of the following reaction conditions, aniline gives p-nitro derivative as the major product?
(i) Acetyl chloride/pyridine followed by reaction with conc.\[\ce{H2SO4 }\] + conc. \[\ce{HNO3}\].
(ii) Acetic anyhdride/pyridine followed by conc.\[\ce{H2SO4}\] + conc.\[\ce{HNO3}\].
(iii) Dil. HCl followed by reaction with conc.\[\ce{H2SO4}\] + conc.\[\ce{HNO3}\].
(iv) Reaction with conc.\[\ce{HNO3}\] + conc.\[\ce{H2 SO4}\].
How will you carry out the following conversions?
Assertion: Hoffmann’s bromamide reaction is given by primary amines.
Reason: Primary amines are more basic than secondary amines.
Reduction of nitro alkanes yields which compound?
Identify the product ‘C’ in the following reaction.
\[\ce{Aniline ->[(CH3CH)2O][Pyridine] A ->[Br2][CH3COOH] B ->[H^+ or OH^-] C}\]
