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प्रश्न
Account for the following:
Gabriel phthalimide synthesis is not preferred for preparing aromatic primary amines.
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उत्तर
Gabriel phthalimide synthesis not prefered for preparing aromatic primary amines because amine formation involves nucleophilic substituion 2 ( ) SN of alkyl halides by the anion formed by the phthalimide. But aryl halides do not undergo nucleophilic substitution with the anion formed by the phthalimide. As nucleophilic substitution reactions are very difficult in aryl halides.
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संबंधित प्रश्न
Give the structure of A, B and C in the following reaction:
\[\ce{CH3CH2I ->[NaCN] A ->[OH-][Partial hydrolysis] B ->[NaOH + Br2] C}\]
Write reactions for the preparation of ethanamine using Gabriel phthalimide synthesis.
Alkyl cyanides on reduction by sodium and ethanol give primary amines. This reaction is called as ____________.
Identify the major product (B).
Which of the following reactions does NOT yield an amine?
In order to prepare a 1° amine from an alkyl halide with simultaneous addition of one \[\ce{CH2}\] group in the carbon chain, the reagent used as source of nitrogen is ______.
Reduction of aromatic nitro compounds using \[\ce{Fe}\] and \[\ce{HCl}\] gives ______.
Which of the following reaction DOES NOT involve Hoffmann bromamide degradation?
Write a short note on Ammonolysis.
Write short notes on the following:
Ammonolysis
