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प्रश्न
Describe Klinefelter’s syndrome.
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उत्तर
- It is a chromosomal disorder caused by an extra X chromosome in males. Thus genotype of individuals is 44 + XXY. They are described as feminized males.
- The extra chromosome is a result of the non-disjunction of the X-chromosome during meiosis in the formation of the ovum.
- Such an individual is male and has overall masculine development. The voice pitch is harsh and has underdeveloped testis. They are tall with long arms, showing feminine development. Voice pitch is harsh and have under developed testis.
- They are tall with long arms, showing feminine development and no spermatogenesis; therefore, individuals are sterile.
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संबंधित प्रश्न
Give any 'two' names of X-linked diseases
During a medical investigation, an infant was found to possess an extra chromosome 21. Describe the symptoms the child is likely to develop later in the life.
What is the reason for the 21st trisomy?
Identify the INCORRECT statement.
Match the Column-I with Column-II and choose the CORRECT answer
| Column-I | Column-II | ||
| P. | Klinefelter syndrome | i. | Mutation in autosomal gene |
| Q. | Thalassaemia | ii. | Mutation sex chromosome linked gene |
| R. | Down syndrome | iii. | Trisomy of autosome |
| S. | Colour blindness | iv. | Trisomy of sex chromosome |
Identify the genetic disorder m which an individual has an overall masculine development, gynaecomastia and is sterile.
Following list indicates various genetic diseases. Identify the diseases that are not caused due to single gene defect.
Huntington's chorea, alkaptonuria, Sickle cell anaemia, Down syndrome, thalassemia, Taysachs disease, Turner syndrome, cystic fibrosis, haemophi Lia, Klinefelter syndrome, albinism
Read the following and answer from given below:
Turner's syndrome is an example of monosomy. It is formed by the union of an allosome-free egg and a normal 'X' containing sperm or a normal egg and an allosome-free sperm. The individual has 2n = 45 chromosomes (44 + X0) instead of 46. Such individuals are sterile females who have rudimentary ovaries, underdeveloped breasts, small uterus, short stature, webbed neck, and abnormal intelligence. They may not menstruate or ovulate. This disorder can be treated by giving female sex hormones to women from the age of puberty to make them develop breasts and have menstruation. This makes them feel more normal.
Turner's syndrome is a/an ______
The technique exployed in human genetic counselling is:
Which of the following is an example of a Mendelian disorder?
