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प्रश्न
Briefly explain the role of the following in providing defence against infection in the human body:
B-cells
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उत्तर
B cells are activated when their B cell receptor (BCR) binds to either soluble or membrane-bound antigens. This activates the BCR to form microclusters and trigger downstream signalling cascades. The micro cluster eventually undergoes a contraction phase and forms an immunological synapse, this allows for a stable interaction between B and T cells to provide bidirectional activation signals. They produce an army of proteins in response to pathogens into our blood to fight with them.
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संबंधित प्रश्न
Why is an antibody molecule represented as H2 L2?
When disease-causing germs enter the bloodstream and produce poisonous substances, what type of chemical substances do lymphocytes produce in response?
An antibody molecule is characterized by its Y-shaped structure composed of which combination of polypeptide chains?
Disulphide bonds link the polypeptide chains of antibodies together. What type of additional stabilisation helps maintain antibody structure?
Which heavy chain type is associated with IgA antibodies?
Which immunoglobulin is involved in mediating Type I hypersensitivity reactions and comprises the smallest percentage of serum?
Which antibody function involves the activation of complement proteins that lead to the lysis of pathogens?
Which immunoglobulin class is responsible for triggering hypersensitivity reactions in response to allergens?
How many primary classes of antibodies exist within the immune system?
Which antibody class is the first to be produced during an immune response to pathogens?
