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प्रश्न
Briefly explain the role of the following in providing defence against infection in the human body:
T-cells
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उत्तर
T-cells are generated in the thymus and are programmed to be specific for one particular foreign particle (antigen). Once they leave the thymus, they circulate throughout the body until they recognize their antigen on the surface of antigen-presenting cells (APCs). The T-cell receptor (TCR) on both helper T-cells and cytotoxic T-cells binds to the antigen as it is held in a structure called the MHC complex, on the surface of the APC. This triggers the initial activation of the T-cells. T-cells themselves do not secret antibodies but help B cells to produce them.
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संबंधित प्रश्न
Explain the structure of immunoglobulin with suitable diagram.
Why is opsonisation efficient in phagocytosis?
A substance that stimulates the production of antibodies is called ______.
In antibody structure, which region is responsible for binding to specific antigens and differs between different antibodies?
Which region of an antibody molecule determines its class and remains consistent within a type of antibody?
IgD antibodies comprise what percentage of serum and serve what primary function?
Which immunoglobulin is involved in mediating Type I hypersensitivity reactions and comprises the smallest percentage of serum?
The process by which antibodies clump bacteria or antigen-bearing cells together, as seen in blood typing reactions, is called:
IgA provides passive immunity through what mechanism, particularly via colostrum and breast milk?
B-lymphocytes produce an army of proteins in response to pathogens. What is the collective name for these defensive proteins?
