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प्रश्न
Briefly explain the role of the following in providing defence against infection in the human body:
B-cells
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उत्तर
B cells are activated when their B cell receptor (BCR) binds to either soluble or membrane-bound antigens. This activates the BCR to form microclusters and trigger downstream signalling cascades. The micro cluster eventually undergoes a contraction phase and forms an immunological synapse, this allows for a stable interaction between B and T cells to provide bidirectional activation signals. They produce an army of proteins in response to pathogens into our blood to fight with them.
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संबंधित प्रश्न
Explain the structure of immunoglobulin with suitable diagram.
Observe the relation between the first two words and then fill in the fourth word.
Histamine: Mast cells :: Antibody: ______.
An antibody molecule is characterized by its Y-shaped structure composed of which combination of polypeptide chains?
Which region of an antibody molecule determines its class and remains consistent within a type of antibody?
Disulphide bonds link the polypeptide chains of antibodies together. What type of additional stabilisation helps maintain antibody structure?
What is the process by which antibodies convert soluble antigens into insoluble complexes for removal from the body?
Which antibody function involves the activation of complement proteins that lead to the lysis of pathogens?
B-lymphocytes produce an army of proteins in response to pathogens. What is the collective name for these defensive proteins?
How many primary classes of antibodies exist within the immune system?
What structural feature connects the two heavy chains and two light chains in an antibody molecule together?
