Question

Distinguish between smooth and rough endoplasmic reticulum.

Answer 1

Character	Smooth endoplasmic reticulum (SER)	Rough Endoplasmic Reticulum (RER)
Definition	Smooth endoplasmic reticulum does not have ribosomes on its membrane.	Rough endoplasmic reticulum possesses ribosomes attached to its membrane.
Organized	It is organized of vesicles and tubules.	It is organized of cisternae and a few tubules.
Found	It is present near the cell membrane.	It is present near the cytoplasm.
Formation	SER gives rise to spherosomes/oleosomes.	RER helps in the formation of lysosomes.
Composed of	It is composed of the tubules.	It is composed of the cisternae.
Synthesis	Synthesises glycogen, lipids, and steroids.	It participates in the synthesis of enzymes and proteins.
Connection	SER may be connected to plasmalemma and is peripheral.	RER is connected with the nuclear envelope and is internal.
Development	Develops from Rough Endoplasmic Reticulum.	It might develop from the nuclear envelope.
Ribophorins	It lacks ribophorins.	It consists of ribophorins and helps ribosomes attach to ER
Provide	Provides vesicles for cis-face of the Golgi apparatus.	Provides proteins and lipids for the Golgi apparatus.
Produces	It produces lipids and proteins.	It produces proteins.