Question

What happens when histamine is discharged in large quantities during anaphylactic shock?

विकल्प

• Gradual appearance of spots over several days

• Formation of blisters that take weeks to heal

• Permanent darkening of the skin

• Wheals may develop all over the skin within a minute or two

Answer 1

When large quantities of histamine are discharged during anaphylactic shock, wheals may develop all over the skin within a minute or two. These are the characteristic urticarial reactions that appear rapidly as histamine causes local vasodilation and increased vascular permeability. The widespread and rapid appearance of wheals is a hallmark sign of systemic anaphylaxis and reflects the simultaneous activation of mast cells throughout the body. This rapid progression is why anaphylactic shock requires immediate emergency treatment.