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प्रश्न
Very Short Answer Question.
Give an example of a chromosomal disorder caused due to nondisjunction of autosomes.
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उत्तर
Down syndrome is an example of a chromosomal disorder caused due to non-disjunction of autosomes.
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संबंधित प्रश्न
What will be the phenotype of progeny, if a carrier haemophilic female marries a normal male?
Attempt any TWO of the following:
‘The gene for sickle cell anaemia in homozygous condition is lethal and produces sickle cell trait in heterozygous carrier’. Explain.
What is the reason for the 21st trisomy?
Following list indicates various genetic diseases. Identify the diseases that are not caused due to single gene defect.
Huntington's chorea, alkaptonuria, Sickle cell anaemia, Down syndrome, thalassemia, Taysachs disease, Turner syndrome, cystic fibrosis, haemophi Lia, Klinefelter syndrome, albinism
The most striking example of point mutation is found in a disease called ______.
Klinefelters’ syndrome is characterised by a karyotype of ______.
Read the following and answer from given below:
Turner's syndrome is an example of monosomy. It is formed by the union of an allosome-free egg and a normal 'X' containing sperm or a normal egg and an allosome-free sperm. The individual has 2n = 45 chromosomes (44 + X0) instead of 46. Such individuals are sterile females who have rudimentary ovaries, underdeveloped breasts, small uterus, short stature, webbed neck, and abnormal intelligence. They may not menstruate or ovulate. This disorder can be treated by giving female sex hormones to women from the age of puberty to make them develop breasts and have menstruation. This makes them feel more normal.
Turner's syndrome is an example of ______
In Down's syndrome, karyotyping has shown that the disorder is associated with trisomy of chromosome number 21 usually due to ______.
Lipoprotein lipase deficiency (LPLD)is a genetic disorder in which a person has a defective gene for lipase. This leads to high triglycerides, stomach pain, and fat deposits under the skin. It may eventually affect the liver, pancreas and may also cause diabetes. The disorder occurs if a child acquires defective genes from both parents (autosomal recessive). ERT (enzyme replacement treatment) is one of the treatments offered to patients with LPLD.
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- What procedure is followed in ERT?
- What could be one possible drawback of ERT?
- How can LPLD be treated using Biotechnology? Elaborate.
Give the genotype of Klinefelter’s syndrome.
