Advertisements
Advertisements
प्रश्न
Klinefelters’ syndrome is characterized by a karyotype of ____________.
विकल्प
XYY
XO
XXX
XXY
Advertisements
उत्तर
Klinefelters’ syndrome is characterized by a karyotype of XXY.
संबंधित प्रश्न
Females with Turners’ syndrome have
Which of the following is not correct?
|
The chromosome number is fixed for all normal organisms leading to species specification whereas any abnormality in the chromosome number of an organism results into abnormal individuals. For example, in humans, 46 is the fixed number of chromosomes both male and female. In males it is '44 + XY' and in females, it is '44 +XX'. Thus the human male is heterogametic, in other words produces two different types of gametes one with '22 + X' chromosomes and the other with '22 + Y' chromosomes respectively. Human female, on the other hand, is homo gametic i.e. produce only one type of gamete with '22 + X' chromosomes only. Sometimes an error may occur during the meiosis of the cell cycle, where the sister chromatids fail to segregate called nondisjunction, leading to the production of abnormal gametes with altered chromosome numbers. On fertilisation, such gametes develop into abnormal individuals. |
(a) State what is aneuploidy. (1)
(b) If during spermatogenesis, the chromatids of sex chromosomes fail to segregate during meiosis, write only the different types of gametes with altered chromosome numbers that could possibly be produced. (1)
(c) A normal human sperm (22 + Y) fertilises an ovum with karyotype '22 +XX'. Name the disorder the offspring thus produced would suffer from and write any two symptoms of the disorder. (2)
OR
(c) Name the best-known and most common autosomal aneuploid abnormality in humans and write any two symptoms. (2)
Which clinical feature is present in approximately 50% of Down's Syndrome cases?
What is the karyotype of Patau Syndrome?
What is the formula for trisomy?
What is the term used to describe the loss of one or more chromosomes due to nondisjunction?
Which numerical abnormality is caused by failure of cytokinesis?
What is the incidence of Edwards Syndrome in relation to other trisomies?
Which trisomy is associated with kidney and lung defects in addition to cardiac abnormalities?
