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How is mature insulin different from pro-insulin secreted by pancreas in humans? - Biology (Theory)

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प्रश्न

How is mature insulin different from pro-insulin secreted by pancreas in humans?

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उत्तर

Sr. No. Feature Pro-insulin Mature insulin
1. Structure Pro-insulin consists of a single polypeptide chain with a C-peptide. Mature insulin consists of two chains (A and B) linked by disulfide bridges.
2. C-peptide In pro-insulin, the C-peptide is present. It is removed during the maturation to form mature insulin.
3. Activity Pro-insulin is inactive. Mature insulin is fully active.
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