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प्रश्न
Differentiate between B-cells and T-cells.
अंतर स्पष्ट करें
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उत्तर
| Aspect | B-cells | T-cells |
| Origin and Development | Produced from stem cells in bone marrow; do not go to thymus for differentiation. Named after “bursa of Fabricius” in birds. | Produced from stem cells in bone marrow; migrate to thymus to differentiate into T-lymphocytes. |
| Location in Lymphoid Tissue | Found primarily in lymphatic nodules. | Found mainly in diffuse lymphoid tissue around lymphatic nodules in lymph nodes and white pulp of spleen. |
| Role in Immunity | Responsible for humoral immune response by producing antibodies. | Responsible for cellular immune response. |
| Response Mechanism | Recognize antigen and produce antibodies to neutralize or mark it for destruction. | Recognize antigen-presenting cells, proliferate, and differentiate into various types (cytotoxic, helper, suppressor) that directly or indirectly destroy infected cells or regulate immune response. |
| Percentage in Blood | About 15% of lymphocytes in blood (less than T-cells). | About 85% of lymphocytes in blood. |
| Circulation | Circulate between lymphoid tissues and blood stream. | Circulate between lymphoid tissues and blood stream. |
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