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प्रश्न
What is the role of topoisomerase I in prokaryotic DNA packaging?
पर्याय
Maintains the supercoiled state of the nucleoid
Introduces negative supercoils into DNA
Synthesises RNA connectors for loop formation
Binds histone proteins to DNA
MCQ
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उत्तर
Topoisomerase I maintains the supercoiled state of the prokaryotic nucleoid by relaxing positive supercoils. This enzyme is essential for balancing the topological stress generated during DNA replication and transcription, preventing excessive positive supercoiling that would inhibit these vital processes.
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