Question

Give the rules of restriction endonuclease nomenclature.

Answer 1

1. The first letter of the enzyme name is taken from the genus of the organism from which it was isolated (capitalised).
2. The next two letters come from the species name (lowercase).
3. If there are multiple strains, a fourth letter from the strain name is added (capitalised).
4. A Roman numeral is used to indicate the order in which the enzyme was isolated from that organism or strain.