Question

Why are Koch's Postulates not applicable to viral pathogens?

विकल्प

• Viruses are too small to be observed under a microscope

• Viruses do not cause disease in any living organisms

• Viruses can only infect plants and not animals

• Viruses cannot be isolated in pure culture due to their obligate intracellular nature

Answer 1

Koch's Postulates cannot be fully applied to viral pathogens because viruses have an obligate intracellular nature, meaning they cannot replicate outside of host cells. They cannot be grown in pure culture in the traditional sense required by the second postulate, as they require living cells for replication. This fundamental biological difference makes standard Koch's Postulate verification impossible for viral diseases.