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प्रश्न
What is the consensus sequence of the –10 region (Pribnow Box) in bacterial promoters?
विकल्प
AATTGG
GGCCAA
TATAAT
CGCGAT
MCQ
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उत्तर
The –10 region, commonly called the Pribnow Box, has the consensus sequence TATAAT. This region is rich in A-T base pairs, which easily melt open due to the weaker hydrogen bonding (two bonds) compared to G-C pairs (three bonds). This facilitates DNA unwinding at the initiation site.
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