Question

The reaction of a primary amine with chloroform and ethanolic KOH is called ______.

विकल्प

• Carbylamine reaction

• Kolbe's reaction

• Reimer-Tiemann reaction

• Wurtz-Fittig reaction

Answer 1

The reaction of a primary amine with chloroform and ethanolic KOH is called Carbylamine reaction.

Explanation:

Carbylamine reaction involves the reaction of a primary amine with chloroform in presence of alcoholic KOH, that leads to the formation of isocyanide, and hence also known as Hofmann isocyanide synthesis.

For example: \[\ce{R - NH2 + CHCl3 + \underset{Alc.}{KOH} -> CHNC + 3KCl + 3H2O}\]