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प्रश्न
Differentiate between Conservative and dispersive replication of DNA.
अंतर स्पष्ट करें
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उत्तर
| Feature | Conservative Replication | Dispersive Replication |
| Main Concept | The entire original DNA double helix remains intact (is “conserved”), and an entirely new double helix is synthesised from scratch. | The original DNA molecule is broken into fragments, and each fragment is replicated. |
| Daughter DNA Composition | After one round of replication, one daughter molecule is 100% old DNA, and the other is 100% new DNA. | Every daughter DNA molecule consists of a patchwork mix of old and new DNA segments along both strands. |
| Unwinding | It was argued that the parental DNA does not split open or unwind at all in this model. | The parental strands break apart and reassemble with new material. |
| Biological Reality | This model is hypothetical and has never been observed in living cells. | This model is also hypothetical and was disproven by experiments. |
| Meselson-Stahl Evidence | Disproven after Generation 1, as it would have produced two separate bands (heavy and light) instead of the intermediate hybrid band actually seen. | Disproven after Generation 2, as it would have continued to produce only a single, progressively lighter band instead of the two distinct bands (hybrid and light) observed. |
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