Question

Why do more children in metro cities suffer from allergies and asthma according to the lifestyle effect?

पर्याय

• Metro cities have higher levels of pathogenic bacteria

• Urban children have genetic predisposition to allergies

• This is mainly linked with the protected environment provided early in life

• Metro areas have higher pollen counts than rural areas

Answer 1

More children in metro cities suffer from allergies and asthma mainly because of the protected environment provided early in life. The hygiene hypothesis suggests that excessive protection from environmental microorganisms and pathogens in infancy prevents normal Th1-mediated immune development, skewing the immune response toward Th2 responses that favor allergic reactions. Urban children experience sterile, climate-controlled environments with minimal exposure to microbial antigens, whereas rural children encounter diverse microorganisms that help properly calibrate immune tolerance.