Question

Which of the following statements are correct about Klinefelter’s Syndrome? 

1. This disorder was first described by Langdon Down (1866). 
2. Such an individual has overall masculine development. However, the feminine development is also expressed. 
3. The affected individual is short statured. 
4. Physical, psychomotor and mental development is retarded. 
5. Such individuals are sterile. 

Choose the correct answer from the options given below:

पर्याय

• Cand D only

• B and E only

• A and E only

• A and B only

Answer 1

B and E only

Explanation:

Klinefelter’s syndrome is a genetic condition where males are born with at least one extra X chromosome, resulting in an XXY genotype. While these individuals typically exhibit overall masculine development, the additional X chromosome leads to the expression of certain feminine traits, such as gynecomastia.

Key facts about the syndrome include:

• Sterility: Affected individuals are generally unable to father children.
• Physical Stature: Unlike some other genetic disorders, those with Klinefelter's are often taller than average rather than short.
• Discovery: The condition was first identified by Dr. Henry Klinefelter.
• Development: While there can be impacts on physical, mental, or psychomotor development, these effects vary significantly and are not present in every case.