Question

Which of the following is NOT an example of a chromosomal disorder?

पर्याय

• Turner's syndrome

• Down's syndrome

• Sickle-cell anaemia

• Klinefelter's syndrome

Answer 1

Sickle-cell anaemia is a Mendelian disorder caused by a point mutation in the β-globin gene, not a chromosomal disorder. Down's, Klinefelter's, and Turner's syndromes are all chromosomal disorders resulting from numerical or structural chromosome abnormalities.